Seclo® MUPS
Omeprazole
Proton Pump Inhibitor (PPI) (Antiulcerant)
MUPS is abbreviation for Multiple-Unit Pellet System. However, from pharmaceutical industry and research perspective, the term in general refers to MUPS compacted into tablets. Thus, the resulting tablets prepared by compaction of modified release coated multiparticulates or pellets are called as MUPS. It is the more recent and challenging technology that combines the advantages of both tablets and pellet-filled capsules in one dosage form.
Indication:
- Duodenal and Gastric ulcers
- NSAID-induced gastric and duodenal ulcers
- Reflux Oesophagitis
- GERD (Gastroesophageal Reflux Disease)
- Eradication of H. pylori with appropriate antibiotics
- Zollinger-Ellison Syndrome
Dosage & Administration:
Adults:
| Indication | Dose | Frequency |
| GERD (Gastroesophageal Reflux Disease) | 20 mg | Once daily for 4 weeks |
| Gastric ulcer | 20 mg | Once daily for 4-8 weeks; in severe cases Twice daily |
| Duodenal ulcer | 20 mg | Once daily for 2-4 weeks; in severe cases Twice daily |
| NSAID-induced ulceration | 20 mg | Once daily for 4-8 weeks |
| Reflux Oesophagitis | 20 mg | Once daily for 4-8 weeks; in severe cases Twice daily |
| H. pylori eradication (Omeprazole MUPS tablet with Amoxicillin and Clarithromycin or Metronidazole) | 20mg | Twice daily for 1 week |
| Zollinger-Ellison Syndrome | 60mg | Once daily; Usual maintenance, 20-120mg daily |
Children over 2 years old:
| Indication | Dose | Frequency |
| Acid regurgitation in GERD (Gastroesophageal Reflux Disease) | 20 mg | Once daily for 2-4 weeks |
| Reflux Oesophagitis | 20 mg | Once daily for 4-8 weeks |
Preparation:
Seclo® MUPS 20 Tablet: Each box contains 30 tablets in Alu-Alu blister pack.
