Nitrocard (Nitroglycerin)

Therapeutic Group : Cardiovascular

Presentation:

Nitrocard Tablet:Each sustained release tablet contains Nitroglycerin USP 2.6 mg.

Indications:

Nitroglycerin is used for the prophylaxis and long term management of angina pectoris, heart failure and myocardial infarction.

Dosage & Administration:

The dosage is determined on the basis of individual requirement depending on the severity of the disease, response to nitroglycerol and development of side-effects. The usual daily dose is initially 1 tablet twice daily. The dose may be gradually increased to 2-3 tablets twice daily.

Contrainidications:

Hypersensitivity to nitrates. Obstructive hypertrophic cardiomyopathy. Low cardiac output secondary to hypovolemia. Inferior myocardial infarction with right ventricular involvement. Raised intracranial pressure. Mitral valve propalpse. Glaucoma.

Side effects:

Headache, flushing, dizziness, postural hypotension, tachycardia may occur.

Drug interaction:

Orthostatic hypotension may occur with the combined use of calcium channel blockers, antihypertensive agents, phenothiazine, and tricyclic antidepressants. Use of alcohol with nitroglycerin may produce severe hypotension and collapse. Oral nitroglycerin may enhance the bioavailability of dihydroergotamine.

Use in special groups:

Use in neonates: Safety and efficacy for use in infants and children have not been established.
Use in children: Safety and efficacy for use in children has not been established.
Use in lactation: Safety and efficacy for use in nursing mother has not been established.
Use in pregnancy: Safety for use during pregnancy has not been established. Use only when clearly needed and when the potential benefits outweigh the unknown potential hazards to the foetus.

Packing:

Nitrocard Tablet: Each box contains 60’s tablets in Alu-Alu blister pack.