Therapeutic Group : Tyrosine Kinase Inhibitor (Oncology) Presentation: ATANIB 40 mg Tablet: Each film coated tablet contains Afatinib Dimaleate INN 59.12 mg equivalent to Afatinib 40 mg. Pharmacology: Mechanism of action: Afatinib covalently binds to the kinase domains of EGFR (ErbB1), HER2 (ErbB2) and HER4 (ErbB4) and irreversibly inhibits tyrosine kinase autophosphorylation, resulting in downregulation of […]
Generic Name: CapecitabineDosage Form: TabletTG Name: Oncology 1. What is Xelocin®?Xelocin® is an anti-metabolite chemotherapeutic agent. 2. How Xelocin® works in our body?Xelocin® converts into 5-Fluorouracil that inhibits the production of the cancerous cells of both DNA and protein that are necessary for the cells to divide and the cancer to grow in size. 3. What are the indications of Xelocin®?Breast […]
Generic Name: DocetaxelDosage Form: Concentrated solution for IV infusionTG Name: Oncology 1. What is Taxedol®?It belongs to a group of drugs called taxanes, which is clinically well established anti-mitotic chemotherapy medication. 2. How Taxedol® works in our body?Taxedol® inhibits microtubular de-polymerization and attenuation of the effects of bcl-2 & bcl-xL gene expression thus hyper stabilizes the structure and causes apoptosis. […]
Generic Name: TamoxifenDosage Form: TabletTG Name: Oncology Tamona® (Tamoxifen) is a non-steroidal, triphenylene-based antineoplastic drug. In breast cancer patients, at the tumour level, Tamoxifen acts primarily as an antioestrogen, preventing oestrogen binding to the oestrogen receptor. If used to the right pa Tamona® (Tamoxifen) is a non-steroidal, triphenylene-based antineoplastic drug. In breast cancer patients, at the tumour level, Tamoxifen acts […]
Generic Name: PaclitaxelDosage Form: Concentrated solution for IV infusionTG Name: Oncology 1. What is Pacli®?Pacli® is a novel anti-microtubule agent. 2. How Pacli® works in our body?Pacli® promotes the assembly of microtubules from tubulin dimers and stabilizes microtubules by preventing de-polymerization. This stability results in the inhibition of the normal dynamic reorganization of the microtubule network that is essential for vital […]
Generic Name: Trastuzumab lyophilizedDosage Form: IV InfusionTG Name: Oncology 1. What is Ogivri®?Ogivri® USFDA & EMA approved first biosimilar Trastuzumab which is a humanised IgG1 monoclonal antibody. 2. How Ogivri® works in our body? 3. What is the indication of Ogivri®? 4. What are the dosage & administration of Ogivri®? 5. What are the adverse effects of Ogivri®? 7. What […]
Generic Name: ErlotinibDosage Form: TabletTG Name: Oncology 1. What is Kaneva®?Kaneva® is a preparation of Erlotinib, which is a type of biological therapy called a tyrosine kinase inhibitor (TKI). 2. How Kaneva® works in our body?Kaneva® is an epidermal growth factor receptor/human epidermal growth factor receptor type 1 (EGFR also known as HER1) tyrosine kinase inhibitor. Kaneva® potently inhibits the intracellular phosphorylation […]
Generic Name: Pegylated Granulocyte Colony Stimulating Factor Injection (PEG-GCSF injection) 6 mg/0.6 mLDosage Form: InjectionTG Name: Oncology 1. What is Fulphila®Fulphila® (6 mg/ 0.6 ml prefilled syringe) is USFDA and EMA approved first Biosimilar Pegfilgrastim which is a granulocyte colony stimulating factor (GCSF) used as a supportive treatment of chemotherapy. 2. How Fulphila® works in our body?Pegfilgrastim is a pegylated, […]