Arovent

ANTIASTHMATICS: Montelukast

Indication:

Montelukast is indicated for the prophylaxis & chronic treatment of asthma in adults & pediatric patients.

Dosage & Administration:

Children (6-14 years of age): 5 mg daily to be taken in the evening.

Adults ( 15 years of age or over): 10 mg daily to be taken in the evening.

The safety & efficacy of Montelukast was demonstrated in clinical trials where it was administered in the evening without regard to the time of food ingestion.

Side Effect:

Generally, Montelukast is well-tolerated. Side effects include dizziness, headache, diarrhea, restlessness, abdominal pain, cough, fever, asthenia, rash & upper respiratory tract infection.

Drug Interaction:

Montelukast has been administered with other therapies routinely used in the prophylaxis & chronic treatment of asthma with no appropriate increase in adverse reactions.

Cytochrome P-450 inducers: Although Phenobarbital induces hepatic metabolism, no dose adjustment for Montelukast is recommended. It is reasonable to employ appropriate clinical monitoring when potent Cytochrome P-450 enzyme inducers, such as Phenobarbital or Rifampin, are co-administered with Montelukast.

Contraindication :

Montelukast is contraindicated to patients with hypersensitivity to any component of this product.

Preparation:

Arovent 5 mg Chewable Tablet: Each tablet contains Montelukast Sodium INN equivalent to Montelukast 5 mg.

Arovent 10 mg Tablet: Each tablet contains Montelukast Sodium INN equivalent to Montelukast 10 mg.