Ametil (Prochlorperazine)

Therapeutic Group : Antiemetic & Antivertigo

Presentation:

Ametil Tablet: Each tablet contains Prochlorperazine Maleate BP 5 mg.

Indications:

Severe nausea, vomiting, vertigo and other psychotic disorders.

Dosage & Administration:

Nausea & vomiting: 5 to 10 mg two to three times daily. 20 mg at starting & 10 mg two hours later or as directed by physicians.
Vertigo and Meniere’s syndrome: 5 mg thrice and max. 30 mg daily. After several weeks dosage may be reduced to 5-10 mg daily or as directed by physicians.
Anxiety: 15-20 mg daily in divided doses initially but this may be increased to a max. 40 mg daily or as directed by physicians.
Schizophrenia and other psychotic disorders: 75 to 100 mg daily, but patients; response varies widely in response and the dosage schedule for Ametil is initially 12.5 mg twice daily for 7 days, the dose per day may be increased at four to seven days intervals until a satisfactory response is obtained. After some weeks, the effective dosage can be reduced.
Children: For the treatment of nausea and vomiting, the dose is 0.25 mg/kg body weight two to three times a day or as directed.

Contrainidications:

Hypersensitivity, jaundice, CNS depression and in cardiovascular diseases.

Side effects:

Drowsiness, dryness of mouth, mild skin rashes, neuromuscular effects, blurred vission, convulsion, difficulty in breathing may occur rarely

Use in special groups:

Use in pregnancy: Safety of this drug in pregnancy has not been established. Pregnant mothers should use this drug only in case of severe nausea & vomiting with recognition of the potential risk.
Use in lactation: Prochlorperazine releases in breast milk. So lactating mothers should not use this drug.

Packing:

Ametil Tablet: Each box contains 500’s tablets in strip pack.