N-Mycin (Natamycin)

Therapeutic Group : Antifungal

Presentation:

Each ml contains Natamycin USP 50 mg

Indications:

N-Mycin sterile ophthalmic suspension is indicated for the treatment of fungal blepharitis, conjunctivitis and keratitis caused by susceptible organisms including Fusarium solani.

Dosage & Administration:

For fungal keratitis: The preferred initial dosage is 1 drop instilled in the conjuntival sac (s) at 1-2 hours interval. The frequency of application can usually be reduced to 1 drop 6-8 times daily after the first 3-4 days. Therapy should generally be continued for 14 to 21 days or until there is resolution of active fungal keratitis. In many cases, it may be helpful to reduce the dosage gradually at 4 to 7 days intervals to assure the replicating fungus has been eliminated. For fungal blepharitis & conjunctivitis: Less frequent initial dosage, 1 drop 4-6 times daily may be sufficient.

Contrainidications:

Natamycin sterile ophthalmic suspension is contraindicated in individuals with a known hypersensitivity to any of its components.

Warning & Precautions:

For topical eye use only. Failure of improvement of keratitis following 7-10 days of administration of the drug suggests that the infection may be caused by a microorganism not susceptible to natamycin.

Side effects:

Local irritation, conjunctival chemosis, hyperemia, etc.

Use in special groups:

Pregnancy: Category C: N-Mycin sterile ophthalmic suspension should be given to a pregnant woman only if clearly needed.

Lactation: It is not known whether this drug is excreted in human milk. Caution should be exercised when natamycin is administered to a nursing mother.

Pediatric: Safety and effectiveness in paediatric patients have not been established.

Packing:

N-Mycin Sterile Ophthalmic Suspension: Each plastic dropper bottle contains 5 ml ophthalmic suspension.