Eroflam
NSAIDs : Etoricoxib
Indication
Eroflam (Etoricoxib) is indicated for relief of pain and inflammation in osteoarthritis, rheumatoid arthritis, other chronic musculoskeletal disorders, acute gout, dysmenorrhoea & following dental surgery.
Contraindication
Etoricoxib is contraindicated to patients with known hypersensitivity to Etoricoxib, patients with active peptic ulceration or gastrointestinal bleeding, patients who have developed signs of asthma, acute rhinitis, oedema or urticaria following the administration of other Non-Steroidal Anti-Inflammatory Drugs (NSAIDs), patient having inflammatory bowel disease, severe hypertension or congestive heart failure to children and adolescents under 16 years of age.
Side Effect
Etoricoxib may cause Dry mouth, Taste disturbance, Mouth ulcers, Flatulence, Constipation, Appetite and weight changes, Chest pain, Fatigue, Paraesthesia, Influenza like syndrome & Myalgia.
Precaution
In patients with advanced renal disease, treatment with Etoricoxib is not recommended. Clinical experience in patients with estimated creatinine clearance of <30 ml/min is very limited. If therapy with it must be initiated in such patients, close monitoring of the patient\’s renal function is advisable.
Pregnancy : As with other drugs known to inhibit prostaglandin synthesis, it should be avoided in late pregnancy because of premature closure of the ductus arteriosus. According to the suggestion of physician it should be used during the first two trimesters of pregnancy only if the potential benefit justifies the potential risk to the foetus.
Lactation : It is not known whether this drug is excreted in human milk.
Dosage & Administration
Adult and adolescent over 16 years:
- Osteoarthritis, Chronic musculoskeletal disorders & Dysmenorrhoea: 60 mg once daily
- Rheumatoid arthritis: 90 mg once daily
- Acute gout & Pain following dental surgery: 120 mg once daily.
