Rabeprazole Sodium Indications Paricel Gastro-resistant tablets are indicated for the treatment of: Pharmacology Rabeprazole suppresses gastric acid secretion by inhibiting the gastric H+/K+-ATPase at the secretory surface of the gastric parietal cell. Because this enzyme is regarded as the acid (proton) pump within the parietal cell, Rabeprazole has been characterized as a gastric proton-pump inhibitor. […]
Montelukast Sodium Indications Reversair is indicated for: Pharmacology Montelukast is a selective and orally active leukotriene receptor antagonist that inhibits the cysteinyl leukotriene receptor (CysLT1). The cysteinyl leukotrienes (LTC4, LTD4, LTE4) are products of arachidonic acid metabolism and are released from various cells, including mast cells and eosinophils. Cysteinyl leukotrienes and leukotriene receptor occupation have […]
Omeprazole Indications Xeldrin is indicated for the treatment of- Pharmacology Omeprazole, a substituted benzimidazole, is an inhibitor of gastric acid secretion. It inhibits gastric acid secretion by blocking hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) enzyme system in the gastric parietal cell. After oral administration, the onset of the antisecretory effect occurs within one hour, with the maximum effect […]
Generic Name : Abiraterone Acetate Indications Zytix is a CYP17 inhibitor indicated in combination with prednisone for the treatment of patients with Pharmacology Abiraterone Acetate is converted in vivo to Abiraterone, an androgen biosynthesis inhibitor, that inhibits 17 α-hydroxylase/C17, 20-lyase (CYP17). This enzyme is expressed in testicular, adrenal, and prostatic tumor tissues and is required […]
Generic Name : Cefuroxime + Clavulanic Acid Indications Zerotil Plus is indicated for the treatment of infections caused by sensitive bacteria. Pharmacology Cefuroxime is a bactericidal second generation cephalosporin antibiotic which is active against a wide range of Gram-positive and Gram-negative susceptible organisms including many beta-lactamase producing strains. Cefuroxime inhibits bacterial cell wall synthesis by […]
Generic Name :Capecitabine Indications Xitabin is a nucleoside metabolic inhibitor with antineoplastic activity indicated for: Pharmacology Capecitabine is a preparation of Capecitabine, an orally-administered chemotherapeutic agent used in the treatment of cancers. Capecitabine is a prodrug, that is enzymatically converted to fluorouracil (antimetabolite) in the tumour, where it inhibits DNA synthesis and slows growth of […]
Generic Name :Paclitaxel Indications Ovarian Carcinoma: Xelpac is indicated as first line and subsequent therapy for the treatment of advanced carcinoma of the ovary. As first line therapy, Xelpac is indicated in combination with cisplatin. Breast Carcinoma: Xelpac is indicated for the adjuvant treatment of node-positive breast cancer administered sequentially to standard doxorubicin-containing combination chemotherapy. […]
Generic Name : Metformin Hydrochloride Extended Release Indications Treatment of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone does not result in adequate glycaemic control. A reduction of diabetic complications has been shown in overweight type 2 diabetic adult patients treated with metformin as first-line therapy after diet failure. […]
Generic Name :Metformin Hydrochloride Indications Treatment of type 2 diabetes mellitus, particularly in overweight patients when dietary management and exercise alone does not result in adequate glycaemic control. A reduction of diabetic complications has been shown in overweight type 2 diabetic adult patients treated with metformin as first-line therapy after diet failure. Pharmacology Metformin is […]
Generic Name :Oxaliplatin Indications Xaloplat, used in combination with infusional 5-fluorouracil/folinic acid, is indicated for: Pharmacology Oxaliplatin undergoes nonenzymatic conversion in physiologic solutions to active derivatives via displacement of the labile oxalate ligand. Several transient reactive species are formed, including monoaquo and diaquo DACH platinum, which covalently bind with macromolecules. Both inter-and intrastrand Pt-DNA crosslinks […]