Zincin (Cinnarizine)

Therapeutic Group : Antiemetic & Antivertigo

Presentation:

Zincin Tablet: Each tablet contains cinnarizine BP 15 mg.

Indications:

It is mainly used for the symptomatic treatment of nausea and vertigo due to Meniere’s disease and other labyrinthine disturbances and for the prevention and treatment of motion sickness. It is also used in the management of various vascular disorders.

1. Cerebral circulatory disorders

a) Prophylaxis and maintenance therapy for symptoms of cerebral vascular spasms and arteriosclerosis such as dizziness, ear buzzing (tinnitus), vascular headache, unsociability and irritability, fatigue, sleep rhythm disorders such as premature awakening, involutional depressions, loss of memory and lack of concentration, incontinence and other disorders due to aging.
b) Sequel of cerebral and cranial trauma.
c) Post-apoplectic disorders.
d) Migraine.
2. Peripheral circulatory disorders: Prophylaxis and maintenance therapy for symptoms of vascular spasms and arteriosclerosis (obliterating arteritis, thromboangitis obliterans, Raynaud’s disease, diabetes, acrocyanosis, perrio, etc.) such as: intermittent claudication, trophic disturbances, pregangrene, trophic and varicose ulcers, paraesthesia, nocturnal cramps, cold extremities.
3. Disorders of balance:
a) Prophylaxis and maintenance therapy for symptoms of labyrinthine arteriosclerosis, vestibular irritability, Meniere’s syndrome, such as vertigo, dizziness, giddiness, syncopal attacks, tinnitus, nystagmus, nausea and vomiting.
b) Prophylaxis of motion sickness.

Dosage & Administration:

Adults : The usual dose is 1 to 2 tablets three times daily.
Children: 5 to 12 years: Half of the adult age.
Motion sickness: 2 Tablets 2 hours before travel then one every 8 hours during journey if necessary.
Peripheral arterial disorders: 75 mg may be given two or three times daily in divided doses.
Disorders of balance: 15 mg three times a day or, as advised by the physician.
After symptomatic relief is obtained, maintenance therapy is indicated for an optimum & lasting results. As Cinnarizine is totally atoxic at therapeutic dose level and also well tolerated, the drug is highly suitable for maintenance therapy.

Contrainidications:

Contraindications are not known.

Side effects:

Side effects such as somnolence and gastrointestinal disturbances are extremely rare. They are transient and may be readily prevented by achieving the optimal dosage gradually. Combination therapy with other drugs is possible. Whenever indicated, caution should be taken in hypotension (high doses). Rarely, extrapyramidal symptoms in elderly on prolonged therapy.

Packing:

Zincin Tablet: Each box contains 250’s tablets in blister pack.