Tendonil

NSAIDs : Acemetacin

Indication

Pain & inflammation associated with musculoskeletal & joint disorders. Such as: Rheumatoid arthritis, Osteoarthritis, Low back pain. and Pain after an operation.

Contraindication

Tendonil® is contraindicated to known hypersensitivity to Acemetacin or Indomethacin; peptic ulcer; safety in children is not established.

Dosage & Administration

The recommended starting dose is 120 mg/day in divided doses, increasing to 180 mg/day in divided doses, depending on patient response. For the treatment of elderly patients, adjustment of dosage is not normally required. However, NSAIDs should be used with particular care in older patients who may be more prone to adverse reactions. Tendonil® should be taken with food, milk or an antacid to reduce the possibility of gastro-intestinal disturbance.

Drug Interaction

Tendonil® reduces the antihypertensive effect of β-blockers. Increased risk of convulsion when used with Quinolone. Concurrent use with Aspirin, NSAIDs or Corticosteroids may increase risk of GI bleeding. Increased risk of Methotrexate toxicity when used together.

Side Effect

Common side effects include anorexia, nausea, vomiting, diarrhea and constipation, peptic ulcer, headache, dizziness & vertigo.

Use Pregnancy Lactation

The safety of this medicine in human pregnancy and lactation has not been established.Therefore, use of this drug during pregnancy and lactation period is not recommended.

Storage

Store in a cool dry place, protected from light. Store below 25 °C. Keep all medicine out of the reach of children.