Naproxen Sodium Indications Xenap is indicated for the relief of sign and symptoms of- It is also indicated for the management of primary dysmenorrhea & pain. Pharmacology As with other non-selective NSAIDs, naproxen exerts it’s clinical effects by blocking COX-1 and COX-2 enzymes leading to decreased prostaglandin synthesis. Although both enzymes contribute to prostaglandin production, […]