Description Voriconazole is an azole antifungal drug. It inhibits the fungal cytochrome P-450 mediated 14 alpha-lanosterol demethylation, an essential step in fungal ergosterol biosynthesis. The accumulation of 14 alpha-methyl sterols correlate with the subsequent loss of ergosterol in the fungal cell wall and may be responsible for the antifungal activity of voriconazole. Presentation Caspa 50 […]
Generic Name: VoriconazoleDosage Form: TabletTG Name: Skin Care 1. What is VIVORI®?VIVORI® (Voriconazole) is a triazole antifungal medication used to treat serious fungal infections. 2. How VIVORI® works in our body?VIVORI® (Voriconazole) binds and inhibits ergosterol synthesis by inhibiting CYP450-dependent 14-alpha sterol demethylase. The inhibition of 14-alpha sterol demethylase results in a depletion of ergosterol in fungal cell membrane. 3. What […]
VoriconazoleAntifungals (Systemic Antifungal) Indication: Voriconazole is indicated in adults and pediatric patients (2 years of age and older) for the treatment of the following fungal infections:– Invasive aspergillosis– Candidemia in non-neutropenic and other deep tissue Candida infections– Esophageal candidiasis– Serious fungal infections caused by Scedosporium apiospermum and Fusarium species including Fusarium solani, in patients intolerant […]