Baclofen Indications SMR is indicated in- Pharmacology Baclofen inhibits both monosynaptic and polysynaptic reflexes at the spinal level by stimulating the GABAB receptors, which inhibits the release of glutamate and aspartate. It may also act at intraspinal sites producing CNS depression. Baclofen also exerts an antinociceptive effect. Dosage & Administration Adult & children over 10 years: […]