Rupatadine Fumarate Indications Rupaset is indicated for the symptomatic treatment of Seasonal & Perennial Allergic Rhinitis and Urticaria. Pharmacology Rupatadine is a long-acting, non-sedative antagonist of histamine H1-receptors. It also antagonizes the platelet activating factor (PAF). Both histamine and PAF cause broncho constriction which leads to an increase in the vascular permeability and act as […]