Tramadol Hydrochloride Indications Pendol is used for the treatment of moderate to severe painful conditions. These include: Pharmacology Tramadol is a centrally acting synthetic analgesic compound. It inhibits the re uptake of neurotransmitters- serotonin and noradrenaline. Thus it modifies the transmission of pain impulses by activating both descending serotonergic pathways and noradrenergic pathways involved in […]