TadalafilPhosphodiesterase type 5 (PDE-5) inhibitor (Anti-erectile dysfunction agent) When sexual stimulation causes the local release of nitric oxide in the corpus cavernosum,nitric oxide then activates the enzyme guanylyl cyclase, which results in increased levels ofcGMP. The increased levels of cGMP in the corpus cavernosum produce smooth musclerelaxation and inflow of blood into the penile tissues, […]