Description Meclizine has antiemetic, anticholinergic and antihistaminic properties. It reduces the sensitivity of the labyrinthine apparatus. The action may be mediated through nerve pathways to the vomiting centre (VC) from the chemoreceptor trigger zone (CTZ), peripheral nerve pathways or other CNS centres. Meclizine has an onset of action of 30 to 60 minutes, depending on […]