Parakil Vet(Ivermectin)

Therapeutic Group: Anthelmintic

Presentation

Parakil vet Injection: Each ml injection contains Ivermectin BP 10 mg.

Description

Ivermectin is derivatives of Avermectins, a family of potent broad-spectrum anthelmintic. Ivermectin binds selectively with high affinity to glutamate-gated chloride ion channels results in the permeability of the cell membrane to chloride ions with hyperpolarization of the nerve or muscle cell, causing paralysis and death of the parasite. It is reliable, long-lasting parasite controller of cattle for effective treatment and control of internal and external parasitic infections and for protecting animals from re-infection.

Indications

Ivermectin injection is indicated for the treatment, control and protect animal from re-infection of the following parasites-

Gastrointestinal Roundworms (adult and fourth-stage larvae): Ostertagiaostertagi, Haemonchusplacei, Trichostrongylusaxei, T. colubriformis, Cooperiaoncophora, C. punctata, C. pectinata, Oesophagostomumradiatum, Bunostomumphlebotomum, Nematodirushelvetianus (adults only) & N. spathiger (adults only).

Lungworms (adults and fourth-stage larvae): Dictyocaulus viviparous

Grubs (parasitic stages): Hypodermabovis& H. lineatum

Sucking Lice: Linognathusvituli, Haematopinuseurysternus&Solenopotescapillatus

Mites (scabies): Psoroptesovis (syn. P. communis var. bovis) &Sarcoptesscabiei var. bovis

Dosage & Administration

Ivermectin injection is indicated for the treatment, control and protect animal from re-infection of the following parasites-
Gastrointestinal Roundworms (adult and fourth-stage larvae): Ostertagiaostertagi, Haemonchusplacei, Trichostrongylusaxei, T. colubriformis, Cooperiaoncophora, C. punctata, C. pectinata, Oesophagostomumradiatum, Bunostomumphlebotomum, Nematodirushelvetianus (adults only) & N. spathiger (adults only).
Lungworms (adults and fourth-stage larvae): Dictyocaulus viviparous
Grubs (parasitic stages): Hypodermabovis& H. lineatum
Sucking Lice: Linognathusvituli, Haematopinuseurysternus&Solenopotescapillatus
Mites (scabies): Psoroptesovis (syn. P. communis var. bovis) &Sarcoptesscabiei var. bovis

Side Effects

Ivermectin is well tolerated at recomended dose. However, a low incidence of soft tissue swelling at the injection site may be observed. These reactions will disappear without any treatment within 30 min-1 hour.

Precautions

This product should not be used in intravenous or intramuscular route.

Use in Pregnancy & Lactation

Ivermectin is safe in pregnant and lactating animal.

Drug Interaction

Barbiturates (such as Phenobarbital, Butalbital), benzodiazepines (such as Clonazepam, Diazepam, Lorazepam), Sodium Oxybate (GHB) and Valproic acid have drug interactions with Ivermectin injection. In that case caution should be applied before using with upper mentioned drugs.

Over Dose

Ivermectin is 10 times safe in ruminants and dogs. However, hives, tingling of feet, weakness, loss of coordination, stomach pain, vomiting, diarrhea, difficult breathing may be reported.

Withdrawal Period

Meat: 21 days & Milk: 28 days.

Storage

Do not store above 30°C, avoid freezing. Store the vial in the carton to protect from light. Keep out of the reach of children.

Commercial Pack

Parakil vet Injection 10 ml: Each commercial box contains 1 vial of 10 ml.
Parakil vet Injection 30 ml: Each commercial box contains 1 vial of 30 ml.