ORBAPIN

Amlodipine 5 mg and Olmesartan 20 mg

CARDIOVASCULAR » CARDIOVASCULAR » ANTIHYPERTENSIVE

INDICATION

ORBAPIN 5/20 is indicated for the treatment of hypertension, alone or with other antihypertensive agents. Lowering blood pressure reduces the risk of fatal and nonfatal cardiovascular events, primarily strokes and myocardial infractions.

DOSAGE AND ADMINISTRATION

The usual starting dose of ORBAPIN 5/20 is one tablet once daily. The starting dosage can be increased after 1 to 2 weeks of therapy to a maximum dose of two tablets of ORBAPIN 5/20 once daily as needed to control blood pressure. Maximum antihypertensive effects are attained within 2 weeks after a change in dose. ORBAPIN 5/20 may be taken with or without food. ORBAPIN 5/20 may be administered with other antihypertensive agents. Initial therapy with ORBAPIN 5/20 is not recommended in patient’s ?75 years old or with hepatic impairment.

Dosage for Renal Impairment: Maximum 20 mg daily in eGFR 20-60 ml/minute/1.73 m2; avoid if eGFR less than 20 ml/minute/1.73 m2.

OR, AS DIRECTED BY PHYSICIAN.

COMPOSITION

ORBAPIN 5/20: Each film-coated tablet contains Amlodipine Besilate BP equivalent to Amlodipine 5 mg and Olmesartan Medoxomil INN 20 mg.