Olpadin 7 (Olopatadine Hydrochloride USP)

Therapeutic Group : Antiallergic

Presentation:

Olopatadine selectively blocks histamine H₁ receptor and stabilizes mast cells. Thus, it prevents histamine binding to its receptors and inhibits mast cell degranulation & histamine release. It also decreases chemotaxis and inhibits the activation of eosinophil.

Pharmacology:

Indications:

Olpadin, Olpadin DS & Olpadin 7 are indicated for the treatment of ocular itching associated with allergic conjunctivitis.

Dosage & Administration:

Olpadin: Instill 1 drop in the affected eye(s) twice daily.
Olpadin DS: Instill 1 drop in the affected eye(s) once daily.
Olpadin 7 : Instill 1 drop in the affected eye(s) once daily.

Contrainidications:

Contraindicated in patients who are hypersensitive to Olopatadine Hydrochloride or any other component of the preparation.

Warning & Precautions:

For ophthalmic use only
To avoid possible contamination of the drops, do not touch the dropper tip or to any surface
Do not wear a contact lens during the treatment
If more than one topical ophthalmic drug is being used, the drugs should be administered at least (5) minutes interval between applications

Side effects:

Blurred vision, temporary burning & stinging, dry eye, foreign body sensation, hyperemia, dysgeusia.

Drug interaction:

Olopatadine has low drug interaction potential as systemic levels of Olopatadine achieved a?er ocular dosing are negligible.

Use in special groups:

Use in Pregnancy There are no adequate and well-controlled studies in pregnant women. Olopatadine should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.

Use in Lactation It is not known whether Olopatadine passes into breast milk. However, caution should be exercised when Olopatadine is administered to a nursing mother.

Use in Pediatric: Safety and effectiveness in children for Olopatadine 0.1% is below the age of 3 years and Olopatadine 0.2% & 0.7% is below 2 years have not been established.
Use in Geriatric No overall differences in safety and effectiveness have been observed between elderly and younger patients.

Storage:

Olpadin & Olpadin DS Eye Drops: Store at 4°-25°C.
Olpadin 7 Eye Drops: Store below 25°C.
Do not use longer than 30 days after first opening.
Keep out of the reach of the children.

Packing:

Olpadin Eye Drops: Each LDPE dropper bottle contains 5 ml Sterile & Pyrogen free eye drops.
Olpadin DS Eye Drops: Each LDPE dropper bottle contains 5 ml Sterile & Pyrogen free eye drops.
Olpadin 7 Eye Drops: Each LDPE dropper bottle contains 5 ml Sterile & Pyrogen free eye drops.