Miki-H
TOPICAL PREPARATION: Miconazole Nitrate +Hydrocortisone
Indication
For the topical treatment of inflamed dermatoses where infection by susceptible organisms and inflammation coexist, e.g. intertrigo and infected eczema. For moist or dry eczema or dermatitis including atopic eczema, primary irritant or contact allergic eczema or seborrheic eczema including that associated with acne. Also for interiginous eczema including inflammatory intertrigo, perianal and genital dermatitis. Organisms which are susceptible to Miconazole are dermatophytes and pathogenic yeasts (e.g. Candida spp.): also many Gram-positive bacteria including many strains of Streptococcus and Staphylococcus.
Contraindication
It should not be used in patients who are hypersensitive to any of the ingredient. It should not be used in tubercular or viral infections of the skin or those caused by gram-negative bacteria.
Dosage & Administration
It should be applied topically to the affected area two or three times daily. The same dosage applies to both adults and children. In infants, long term continuous topical corticosteroid therapy should be avoided. Occlusive dressing is usually only necessary in the case of nail lesions. Once the inflammatory symptoms have disappointed (after about 7 days) treatment can be continued where necessary with Miki-H cream.
Side Effect
Rarely local sensitivity may occur. Topically applied corticosteroids can be absorbed in sufficient amounts to produce systemic effects.
Precaution
It should be used with caution when applied to extensive surface areas or under occlusive dressings including baby napkins. Application to the extensive surface areas of the face should be avoided. In infants, long term continuous topical corticosteroid therapy should be avoided. Adrenal suppression may occur even without occlusion.
Administration of corticosteroids to pregnant animal at high doses can cause abnormalities of fetal development. Topical steroids should not be extensively used in pregnancy.
Drug Interaction
Amphotericin antagonises effect of Miconazole.
Presentation
Miki-H Cream: Each pack has a tube containing 10 gm of the cream.
