Lotepred Plus (Loteprednol Etabonate & Tobramycin)

Therapeutic Group : Antibiotic + Steroid

Presentation:

Lotepred Plus Sterile Ophthalmic Suspension: Each ml contains Loteprednol Etabonate INN 5 mg and Tobramycin USP 3 mg.

Indications:

Lotepred-Plus is indicated for steroid-responsive inflammatory ocular conditions for which a corticosteroid is indicated and where superficial bacterial ocular infection or a risk of bacterial ocular infection exists. It is also effective in post-operative inflammation.

Dosage & Administration:

Instill 1 drop of Lotepred-Plus into the conjunctival sac of the eye(s) every 4 to 6 hours.

Contrainidications:

Contraindicated in most viral diseases of the cornea and conjunctiva. Also contraindicated in individuals with known or suspected hypersensitivity to any of the ingredients of this preparation and to other corticosteroids.

Warning & Precautions:

For ophthalmic use only. If this product is used for 10 days or longer, intraocular pressure should be monitored. Fungal infections of the cornea are particularly prone to develop coincidentally with long-term use of steroid topically. Prolonged use may result in overgrowth of nonsusceptible organisms including fungi. If superinfection occurs, appropriate therapy should be initiated. Cross-sensitivity to other aminoglycoside antibiotics may occur.

Side effects:

Increased intraocular pressure, burning & stinging upon instillation, vision disorders, discharge, itching, photophobia, headache and other unspecified eye disorders may occur.

Use in special groups:

Use in pregnancy: There are no adequate and well-controlled studies in pregnant women. Lotepred-Plus should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in lactation: Caution should be exercised when Lotepred-Plus is administered to a nursing mother.
Use in children: Safety and effectiveness in pediatric patients have not been established.

Packing:

Lotepred Plus Sterile Ophthalmic Suspension: Each plastic dropper bottle contains 5 ml sterile ophthalmic suspension.