FIRMAC PLUS(Erythromycin+Sulphadiazine + Trimethoprim)
Therapeutic Group: Anti Bacterial
Presentation
Firmac Plus: Each gram powder contains Erythromycin Thiocyanate INN 180 mg, Sulfadiazine BP 150 mg and Trimethoprim BP 30 mg.
Description
The ingredients of Erythromycin, Sulphadiazine and Trimethoprim are antifolate drug that inhibits bacterial protein synthesis, antifolate drugs and able to kill bacteria. The combination has synergistic activity against wide spectrum of microorganisms, effective at low dose, besides gram positive and gram negative baeteria it is effective against mycolplasma, campylobacter, ricketssia and Chlamydia. The combination have 90-100% bioavailability which is very effective to kill bacteria.
Indications
Erythromycin, Sulphadiazine & Trimethoprim is indicated in infectious coryza, fowl cholera, fowl typhoid, pullorum disease, chronic respiratory disease (CRD), Colisepticemia and enteritis of poultry.
Dosage & Administration
0.5-1 g/litter of drinking water continues for 3-5 consecutive days, dose may be increased or decreased according to the severity of infection or as directed by the registered veterinarian.
Side Effects
The combination is well tolerated and does not show any side effect in poultry at the recommended dose.
Precautions
Treatment would be stopped before 5 days of slaughter.
Use in Pregnancy & Lactation
Sufficient clinical data not available.
Drug Interaction
Macrolide antibiotic should not be used with Chloramphenicol, Tylosin, or the Lincosamides.
Over Dose
Over dosage may lead to impaired excretion, diarrhea, abdominal pain and neurotoxicity.
Withdrawal Period
Storage
Protect from light & keep in a cool and dry place. Keep out from reach of children.
Commercial Pack
Firmac Plus: Each sachet contains 100 g powder.