Dynase

Generic Name: Azelastine hydrochloride 137 µp and Fluticasone propionate 50 µp
Dosage Form: Nasal Spray
TG Name: Respiratory

1. What is Dynase^®?
Dynase^® is a nasal spray which is the preparation of Azelastin Hydrochloride 137 mcg & Fluticasone propionate 50 mcg.

2. How Dynase^® works in our body?
Azelastine is an antihistamine that works by blocking certain natural substances called histamines that are responsible for allergic symptoms. Fluticasone belongs to a class of drugs known as corticosteroids. It works by reducing swelling (inflammation) in the nasal passages. Together Dynase^® targets six allergic substances for inflammatory response, i.e histamine, platelet activating factor, interleukins, prostaglandins, triptase and leukotriene and give complete relief from allergic symptoms.

3. What is the indication of Dynase^®?
Dynase^® is used to relieve seasonal allergy symptoms of the nose such as sneezing, runny nose, itchy nose, blocked nose, sinus pain and congestion and watery eye with redness.

4. What are the dosage & administration of Dynase^®?
6 years and older: one spray in each nostril twice daily morning and evening
Duration of treatment: subject to period of allergenic exposure

5. What are the contraindications of Dynase^®?
Hypersensitivity to the active substances.

6. What are the adverse effects of Dynase^®?
The most common adverse reactions (≥2% incidence) are: dysgeusia, epistaxis and headache.

7. What would be the storage condition of Dynase^®?
Do not store above 30° C. Keep in a dry place. Protect from light. Keep out of the reach of children.