Bortez

Bukof

/in /by
Bortez

Generic Name:Butamirate Citrate

Indications

Bukof is used to relieve dry (non-productive) cough. Dry cough may be caused by a recent viral infection. Bukof is also used for pre & post-operative cough sedation in patients who will undergo surgical procedures and bronchoscopy. It can be used in the acute cough of any etiology, whooping cough and cough due to acute lower respiratory tract infections (tracheitis, laryngitis, bronchitis) etc.

Pharmacology

Butamirate Citrate acts directly on the brain’s cough center to suppress cough. Butamirate Citrate is safe and non-sedating which is neither chemically nor pharmacologically related to opium alkaloids. Butamirate Citrate is rapidly and completely absorbed after oral administration. Maximum concentration is reached within 9 hours with the sustained-release tablet. This is extremely protein-bound and plasma elimination half-life is about 13 hours. The active metabolites of Butamirate Citrate have also antitussive action.

Dosage & Administration

Use in adult:

  • Butamirate Citrate 50 mg tablet: 2-3 tablets daily.
  • Butamirate Citrate syrup: 15 ml 4 times daily.

Use in children & adolescents:
Butamirate Citrate 50 mg tablet:

  • Adolescent over 12 years old: 1-2 tablets daily.

Butamirate Citrate syrup:

  • Children (3-6 yrs): 5 ml 3 times daily.
  • Children (6-12 yrs): 10 ml 3 times daily.
  • Adolescent: 15 ml 3 times daily.

Butamirate Citrate pediatric drops:

  • Children ( 2 months- 1 yrs): 0.50 ml 4 times daily.
  • Children (1-3 yrs): 0.75 ml 4 times daily.