Benosol Emulsion

Benzyl Benzoate

Indications

Benosol is indicated for-

• Scabies
• Pediculosis pubis and capitis

Pharmacology

Benzyl Benzoate is used in the treatment of ectoparasites such as scabies and pediculosis. Benzyl benzoate in concentrations of 10-20% v/v is toxic to sarcoptes scabiei as well as pediculosis. In vitro, the sarcoptes mite is killed in 5 minutes in benzyl benzoate. It’s mechanism of action is unclear but in view of its effects on vertebrates, it is thought that it may act on the nervous system of the parasite.

Dosage & Administration

Scabies: After a hot bath and drying, it is applied to the whole body except the head and face. If the application is thorough, one treatment should suffice, but the possibility of failure is lessened if a second application is made within 5 days of the first. Alternatively, Scabisol can be applied to the whole body, except the head and face, on three occasions at 12 hourly intervals. The patient has a hot both 12 hours after the last application and changes to clean clothes and sheets.

Pediculosis: The affected region is coated with Scabisol followed by a wash 24 hours later with soap and water. In severe cases this procedure may need to be repeated two or three times. An examination should always be made a week after the last treatment to confirm disinfestation.

USE IN CHILDREN: It can be diluted with an equal quantity of water for older children and with three parts of water for babies.

* চিকিৎসকের পরামর্শ মোতাবেক ঔষধ সেবন করুন‘

Interaction

No hazardous interactions have been reported.

Contraindications

It should not be used on the face due to its irritant effect on the risk, and should not be used on broken or irritant skin.

Side Effects

It is irritant to the eyes and mucous membrane and it may be irritant to the skin. Hypersensitivity reactions have been reported. Systemic symptoms have been reported following excessive topical use.

Pregnancy & Lactation

There is inadequate evidence of the safety of Benzyl benzoate in human pregnancy, but it has been widely used without apparent ill consequence. Nevertheless, it should not be used during pregnancy unless considered essential. Breast feeding should be suspended during treatment with Benzyl benzoate. Feeding may be restarted after the emulsion has been washed off the body.

Precautions & Warnings

It causes little skin irritation, but may cause a transient burning sensation. This is usually mild but can occasionally be severe in sensitive individuals. In the event of a severe skin reaction, the preparation should be washed off using soap and warm water. It is also irritating to the eyes, therefore these should be protected if it is applied to the scalp.

Therapeutic Class

Parasiticidal preparations, Topical Antifungal preparations

Storage Conditions

Keep below 25°C temperature, away from light & moisture. Keep out of the reach of children.