Antikof Syrup
Guaifenesin + Levomenthol + Diphenhydramine
Indications
This syrup is indicated for the relief of cough, associated congestive symptoms and aiding restful sleep
Composition
Each 5 ml syrup contains-
- Gualfonosln BP 100 mg
- Levomenthol BP 1.1 mg
- Diphenhydramine Hydrochlorldo BP 14 mg
Pharmacology
Guaifenesin is reported to reduce the viscosity of tenacious sputum end is used as an expectorant. Levomenthol has mild local anesthetic and decongestant properties. Diphenhydramine Hydrochloride possesses antitussive, antihistaminic, and anticholinergic properties.
Dosage & Administration
For adults and children over 12 years: 2 teaspoonfuls syrup 4 times a day or as directed by the physicians. Do not take more than 8 teaspoonful syrup in 24 hours.
Use in Children & Adolescents: The efficacy and safety of Guaifenesin have not been established in pediatric patients and adolescents.
Interaction
This syrup contains Diphenhydramine Hydrochloride and therefore may potentiate the effects of alcohol, and other CNS depressants. As Diphenhydramine Hydrochloride possess some anticholinergic activity, the effects of anticholinergics (e.g. some psychotrophic drugs and atropine) may be potentiated by Antikof. This may result in tachycardia, mouth dryness, gastrointestinal disturbances (e.g. colic), urinary retention and headache.
Contraindications
This syrup is contraindicated in individuals with known hypersensitivity to the product or any of its components. This medicine should not be administered to patients who have received treatment with MAOIs within last two weeks.
Side Effects
This syrup may cause drowsiness, dizziness, nausea and vomiting, gastro-intestinal disturbance, dry mouth, nose and throat difficulty in urination or blurred vision.
Pregnancy & Lactation
As with any other medicine, care should be taken In administration during pregnancy. This product has not been associated with adverse effects in the human fetus or suckling infant.
Precautions & Warnings
This syrup may cause drowsiness; if affected, individuals should not drive or operate machinery. Diphenhydramine Hydrochloride should not be taken by individuals with narrow-angle glaucoma or symptomatic prostatic hypertrophy. Antikof should not be used for persistent or chronic cough, such as occurs with asthma, or where cough is accompanied by excessive secretions unless directed by a physician.
Overdose Effects
When taken in excess, Guaifenesin may cause renal calculi. Treatment of overdose should be symptomatic and supportive.
Therapeutic Class
Combined cough expectorants
Storage Conditions
Store at a temperature not exceeding 30° C in a dry place. Protect from light & moisture. Keep out of the reach of children.
