AFM (Fluorometholone)

Indications

For steroid responsive inflammation of the palpebral and bulbar conjunctiva, cornea and anterior segment of the globe.

Dosage & Administration

1 drop instilled into the conjunctival sac 2-4 times daily. During the initial 24 to 48 hours the dosage may be safely increased to 1 drop every hour. Care should be taken not to discontinue therapy prematurely. Shake well before use.

Contrainidications

Acute superficial herpes simplex keratitis, fungal diseases of ocular structures, vaccinia, varicella and most other viral diseases of the cornea and conjunctiva, tuberculosis of the eye, hypersensitivity to the component of this mediaction.

Side effects

Elevation of intraocular pressure with possible development of glaucoma, and frequent optic nerve damage, posterior subcapsular cataract formation, secondary ocular infection from pathogens liberated from ocular tissues, perforation of the globe delayed wound healing.

Description

Corticosteroids, such as fluorometholone, inhibit the inflammatory response to a variety of inciting agents. They inhibit edema, fibrin deposition, capillary dilation, leukocyte migration, phagocytic activity, capillary proliferation, fibroblast proliferation, deposition of collagen, and scar formation associated with inflammation.