Dexamox (Moxifloxacin + Dexamethasone Phosphate)

Therapeutic Group : Antibiotic + Steroid

Presentation:

Dexamox Eye Drops: Each ml contains Moxifloxacin Hydrochloride BP equivalent to Moxifloxacin 5 mg & Dexamethasone Sodium Phosphate USP equivalent to Dexamethasone Phosphate 1 mg.

Preservative: Sorbitol BP 0.2%

Indications:

Dexamox Eye Drops is indicated in the treatment of eye infections caused by susceptible microorganisms and in the prevention of inflammation and bacterial infection that may occur after eye surgery.

Dosage & Administration:

In the prevention of infection and post-surgical ocular inflammation: Instill 1 drop, 4 times a day, in the eye to be operated, from 1 day before surgery until 15 days after surgery. In patients undergoing cataract surgery: The day of surgery instill the medication immediately after eye surgery. In patients undergoing LASIK refractive surgery: On the day of surgery instill the medication at least 15 minutes after ocular surgery. In eye infections caused by susceptible microorganisms: Instill 1 drop, 4 times a day, for up to 7 days.

Contrainidications:

Hypersensitivity to quinolones. Epithelial herpes simplex keratitis (dendritic keratitis), vaccinia, varicella & other viral diseases of cornea & conjunctiva. Mycobacterial infection of the eye. Fungal diseases of ocular structures. Glaucoma & diseases causing thinning of cornea or sclera.

Warning & Precautions:

– For ophthalmic use only
– Solution should not be injected under the conjunctiva, nor introduced directly into the anterior chamber of the eye
– Prolonged use of steroids may result in ocular hypertension

Side effects:

Moxifloxacin: Conjunctivitis decreased visual acuity, dry eye, keratitis, Ocular discomfort, hyperemia, pain, Subconjunctival hemorrhage and tearing.

Dexamethasone: Visual acuity & field defects, cataract formation, secondary ocular infection following suppression of host response & perforation of the globe.

Use in special groups:

Use in pregnancy:
There are no adequate and well-controlled studies in pregnant women. Moxifloxacin & Dexamethasone combination eye drops should be used during pregnancy only if the potential benefit justifies the potential risk to the fetus.
Use in elderly:
No change in dosage is required when the product is administered in elderly patients.
Use in Children:
The efficacy and safety of Moxifloxacin & Dexamethasone combination eye drops in pediatric patients have not been established.
Use in lactation:
Caution is advised when Moxifloxacin & Dexamethasone combination eye drops is given to nursing women.

Packing:

Dexamox Eye Drops: Each plastic dropper bottle contains 5 ml Sterile & Pyrogen free Eye Drops.