Aspin-Plus (Aspirin + Clopidogrel)

Therapeutic Group : Cardiovascular

Presentation:

Aspin-Plus Tablet: Each film coated tablet contains Clopidogrel (as bisulphate) USP 75 mg plus Aspirin BP 75 mg.

Indications:

Aspin-Plus is indicated for the reduction of thrombotic events as follows:
Recent MI, recent stroke or established peripheral arterial disease: For patients with a history of recent myocardial infarction (MI), recent stroke or established peripheral arterial disease, Aspin-Plus has been shown to reduce the rate of a combined endpoint of new ischemic stroke, new MI (fatal or not) and other vascular death.
Acute coronary syndrome: For patients with acute coronary syndrome including patients who are to be managed with medically and those who are to be managed with percutaneous coronary intervention, Aspin-Plus has been shown to decrease the rate of a combined endpoint of cardiovascular death, MI, stroke or refractory ischemia.

Dosage & Administration:

The recommended daily dose is one tablet.
Aspin-Plus can be administered with or without food.

Contrainidications:

The use of Aspin-Plus is contraindicated in the following conditions:
Hypersensitivity to the drug substance or any component of the product.
Active pathological bleeding such as peptic ulcer or intracranial ulcer.

Warning & Precautions:

Use with caution in patients at increased risk of bleeding from trauma, surgery or other pathological conditions.
Severe hepatic impairment: Use with caution in patients with severe hepatic disease.

Side effects:

This drug is generally well tolerated. Side effects that have been reported include chest pain, fatigue, edema, headache, dizziness, abdominal pain, dyspepsia, diarrhea, nausea, and depression.

Drug interaction:

Use caution with phenytoin, tamoxifen, tolbutamide, warfarin, torsemide, fluvastatin, and non-steroidal anti-inflammatory agents.

Use in special groups:

Pregnancy: Aspin-Plus should be used during pregnancy only if clearly needed.
Lactation: It is not known whether this drug is excreted in human milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the nursing woman.

Packing:

Aspin-Plus Tablet: Each box contains 30’s tablets in alu-alu blister pack.