Asmolex-L

Levosalbutamol

Indications

Asmolex-L is indicated for the treatment or prevention of bronchospasm in adults, adolescents, and children 6 years of age and older with reversible obstructive airway disease.

Dosage & Administration

Tablet
Adults and children above 12 years: 1-2 mg three times daily.
Children (6 -11 years): 1 mg three times daily.
Syrup
Adults and children above 12 years: 5-10 ml three times daily.
Children (6 -11 years): 5 ml three times daily.

Contrainidications

Hypersensitivity to any of the components of the formulation.

Warning & Precautions

Particular caution is advised in acute severe asthma as this effect may be potentiated by hypoxia and by concomitant treatment with xanthine derivatives, steroids and diuretics. Serum potassium levels should be monitored in such situations. Oral Levosalbutamol should be used with caution in patients with cardiovascular disorders, especially coronary insufficiency, cardiac arrhythmias or hypertension. Levosalbutamol can be used with caution after myocardial infarction.

Side effects

Potentially serious side effects like hypokalamia may result from ß-2 agonist therapy. This effect may be potentiated by hypoxia. The other likely side effects are gastrointestinal disturbances such as nausea, vomiting, burning substernal or epigastric pain and diarrhoea. In some cases nervousness, headache, dizziness, fatigue and sleeplessness may occur.

Description

L-Salbutamol is a single isomer ß-2 agonist that differs from racemic salbutamol by elimination of S-salbutamol. L-Salbutamol is an effective bronchodilator whose primary mechanism of action is unimpeded by (S)-salbutamol. Thus, when compared with racemic salbutamol, clinically comparable bronchodilation can be achieved with doses that substantially lessen beta-mediated side effects.