Rimodep(St. John’s Wort)

Therapeutic Group: Herbal and Nutraceuticals

Presentation

Each capsule contains 300 mg standardized extract of St John’s Wort.

Description

St. John’s Wort is an herb which is most commonly used to treat for mild to moderate depression and conditions that sometimes go along with depression such as anxiety, tiredness, loss of appetite and insomnia. The main components of St. John’s Wort are Hypericin and Hyperforin which are responsible for its effects against depression. Although the exact mechanism of action of St. John’s Wort is unknown but it may inhibit the reuptake of Serotonin and Noradrenaline, inhibit Monoamine Oxidase (MAO), up-regulate Serotonin receptor, and reduce depression.

Indications

St. John’s Wort is used to treat mild to moderate depression, anxiety and insomnia.

Dosage & Administration

The recommended dose of St. John’s Wort in adult is 300 mg three times daily

Side Effects

St. John’s Wort is generally safe for most people. It sometimes may cause dry mouth, dizziness, constipation and diarrhea.

Precautions

St. John’s Wort should be used cautiously with drugs metabolized by Cytochrome P450 and drugs that lower the seizure threshold.

Use in Pregnancy & Lactation

St. John’s Wort is not recommended for use during pregnancy.Because of the possible risk to the infant, breast-feeding while using this drug is not recommended.

Drug Interaction

Symptoms of St. John’s Wort overdose may include dry mouth, dizziness and diarrhea.