Alurol Vet(Allopurinol)
Therapeutic Group: Anti Gout
Presentation
Alurol Vet: Each gm powder contains Allopurinol USP 50 mg
Description
Allopurinol is a xanthine oxidase inhibitor which is administered orally. It acts on purine catabolism without disrupting the biosynthesis of purine. It reduces the production of uric acid by inhibiting the biochemical reactions immediately preceding its formation. Allopurinol is a structural analogue of the natural purine base, hypoxanthine. It is an inhibitor of xanthine oxidase, the enzyme responsible for the conversion of hypoxanthine to xanthine and xanthine to uric acid, the end product of purine metabolism
Indications
Alurol Vet is indicated for prevention and treatment of high blood uric acid level and gout, prevents deposition of urate crystal in kidney, serous membranes of liver, heart, air sac and joints of poultry.
Dosage & Administration
Poultry- 25 mg/kg body or 2.5 gm/liter water for 3-5 days, or as directed by registered veterinarian.
Side Effects
The most frequent adverse reaction to Allopurinol is skin rash such as, pruritic maculopapular skin eruptions, sometimes scaly or exfoliative.
Precautions
Before you use discuss with your doctor if you are allergic to it or its ingredients.
Use in Pregnancy & Lactation
Sufficient clinical data is not available.
Drug Interaction
Anticoagulant: Allopurinol prolongs the half life of the anticoagulant, dicumarol.
Diuretic: Concomitant use of Allopurinol and thiazide diuretics may contribute to the enhancement of Allopurinol toxicity.
Cytotoxic agent: Enhanced bone marrow suppression by cyclophosphamide and other cytotoxic agent has been reported among patients with neoplastic disease.
Over Dose
Over dosage may cause diarrhea, abdominal pain and neurotoxicity.
Withdrawal Period
Sufficient data is not available.
Storage
Protect from light & keep in a cool and dry place. Keep out of reach of children.
Commercial Pack
Alurol Vet 100gm: contains 100 gm powder in a sachet.
Alurol Vet 500gm: Each container contains 500 gm powder in a sachet.
